Assoc. Prof. Victoria Vitkova, Ph.D.
E-mail: victoria@issp.bas.bg
research activities:
lyotropic liquid crystals; biophysics of model and bio-membranes;
protein-lipid interactions; cellular biophysics; microfluidics; rheology
obtained degrees:
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Ph.D. degree, May 2002, University of Rennes 1 – Ph.D. Thesis entitled “Elasticité, perméabilité et morphologie des bicouches lipidiques en présence d’additifs hydrophiles et amphiphiles” |
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MSc degree in Physics, January 1997, Quantum Electronics and Laser Technique, Faculty of Physics, University of Sofia – M.Sc. Thesis entitled “Pulse electronic holography” |
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MSc degree in Biophysics, September 1996, Biophysics and Radiobiology, Faculty of Biology, University of Sofia – M.Sc. Thesis entitled “Influence of divalent ions and polylysine on the electrokinetic and light scattering properties of spinach thylakoids” |
qualification:
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March 2011, March-May 2010, March 2009, June-August 2008, October-November 2007, May-June 2007, September-December 2006 – visiting scientist in LIPhy - Laboratoire Interdisciplinaire de Physique (former: Laboratoire de Spectrométrie Physique), CNRS UMR 5588, Université Joseph Fourier – Grenoble, France |
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March 2003 – May 2004 – Post-doctoral Fellow in Laboratoire de Spectrométrie Physique, CNRS UMR 5588 (Grenoble, France) |
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January 2003 – Research Fellow in the Laboratory of Liquid Crystals at the Institute of Solid State Physics – Bulgarian Academy of Sciences |
selected publications:
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V. Vitkova and A. G. Petrov, Lipid bilayers and membranes: material properties, in A. Iglič and J. Genova, editors: Advances in Planar Lipid Bilayers and Liposomes vol. 17 Burlington: Academic Press (2013) pp. 89-138 |
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D. Mitkova, A. Stoyanova-Ivanova, Yu. A. Ermakov and V. Vitkova, Experimental study of the bending elasticity of charged lipid bilayers in aqueous solutions with pH5, J. Phys.: Conf. Ser. 398 012028 (2012) |
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V. Vitkova, A. Farutin, B. Polack, C. Misbah, and T. Podgorski, Erythrocyte dynamics in flow affects blood rheology, J. Phys.: Conf. Ser. 398 012027 (2012) |
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A. Stoyanova-Ivanova, D. Mitkova, St. Georgieva, and V. Vitkova, Lipid bilayers as biocompatible model systems – does the acidity of the aqueous solution alter the membrane elasticity?, Adv. Nat. Sci.: Theory and Applications 1 (1) 29-35 (2012) |
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V. Vitkova, D. Mitkova, N. Kozarev, A. Stoyanova-Ivanova, and I. Bivas, Bending rigidity of lipid membranes and the pH of the aqueous surroundings, C. R. Acad. Bulg. Sci. 65 (3) (2012) 329 |
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V. Vitkova and C. Misbah, “Dynamics of lipid vesicles – from thermal fluctuations to rheology” in Advances in Planar Lipid Bilayers and Liposomes, Elsevier, Amsterdam (2011) 257-292 |
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K. Antonova, V.Vitkova, M. D. Mitov, “Deformation of giant vesicles in AC electric fields – dependence of the prolate-to-oblate transition frequency on vesicle radius”, Europhys. Lett. EPL 89: 38004 (2010) |
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V. Vitkova, K. Antonova, G. Popkirov, M.D. Mitov, Yu.A. Ermakov, and I. Bivas “Electrical resistivity of the liquid phase of vesicular suspensions prepared by different methods”, J. Phys.: Conf. Ser. 253 012059 (2010) |
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K. Antonova, V. Vitkova, G. Popkirov, T. Tenev, I. Miloushev, and I. Bivas, “Experimental study of the electrically induced optical birefringence in densely packed suspensions of giant lipid vesicles” J. Phys.: Conf. Ser. 012058 (2010) |
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V. Vitkova, G. Coupier, M.-A. Mader, B. Kaoui, C. Misbah and T. Podgorski, “Tumbling of Viscous Vesicles in a Linear Shear Field Near a Wall” J. Optoel. Adv. Mater. 11 (9) pp. 1218-1221 (2009) |
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J. Genova, A. Zheliaskova, V. Vitkova, M. D. Mitov, “Stroboscopic Illumination Study of the Dynamics of Fluctuating Vesicles” J. Optoel. Adv. Mater. 11 (9) pp. 1222-1225 (2009) |
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V. Vitkova, M.-A. Mader, B. Polack, C. Misbah and T. Podgorski, “Micro-macro link in rheology of erythrocyte and vesicle suspensions”, Biophys. J. 95 (7) L33-L35 (2008) |
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V. Vitkova, V. Doltchinkova, M. D. Mitov and I. Bivas, “Membrane bending elasticity of human erythrocyte ghosts”, J. Optoel. Adv. Mater. 9 (2) pp. 431-434 (2007) |
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V. Vitkova, P. Méléard, T. Pott and I. Bivas, “Alamethicin influence on the membrane bending elasticity”, Eur. Biophys. J. 35, pp. 281-286 (2006) |
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V. Vitkova, J. Genova, M.D. Mitov, and I. Bivas, “Sugars in the aqueous phase change the mechanical properties of lipid mono- and bilayers”, Mol. Cryst. Liq. Cryst. 449, pp. 95–106 (2006) |
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M.Mader, V. Vitkova, M. Abkarian, A. Viallat and T. Podgorski, “Dynamics of viscous vesicles in shear flow”, Eur. Phys. J. E 19, pp.389-397 (2006) |
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V. Vitkova, M. Mader, T. Biben, and T. Podgorski, “Tumbling of Deformable Lipid Vesicles, Enclosing a Viscous Fluid under a Shear Flow”, J. Optoel. Adv. Mater. 7 (1), pp. 261-264 (2005) |
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J. Genova, V. Vitkova, L. Aladgem, M. D. Mitov, “The stroboscopic illumination gives new opportunities and improves the precision of the bending elastic modulus measurement”, J. Optoel. Adv. Mater. 7 (1), pp. 257-260 (2005) |
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V. Vitkova, J. Genova, M.D. Mitov, and I. Bivas, “Mechanical Properties of Lipid Mono- and Bilayers in the Presence of Small Carbohydrates in the Aqueous Phase”, C. R. Acad. Bulg. Sci. 57 (6), pp. 1-15 (2004) |
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V. Vitkova, J. Genova and I. Bivas, “Permeability and Hidden Area of Lipid Bilayers”, Eur. Biophys. J. 33 (8) pp 706-714 (2004) |
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V. Vitkova, M. Mader, and T. Podgorski, “Deformation of vesicles flowing through a capillary”, Europhys. Lett. 68 (3), pp. 398-404 (2004) |
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V. Vitkova, J. Genova, O. Finogenova, Y. Ermakov, M.D. Mitov, and I. Bivas, “Surface Charge Effect on the Lipid Bilayer Elasticity”, C. R. Acad. Bulg. Sci. 57 (11), pp. 25-30 (2004) |
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V. Vitkova, J. Genova and P. Méléard, “Influence of alamethicin on the passive water permeability of model lipid membranes and on the morphology of giant lipid vesicles”, J. Mater. Sci.: Mater. El. 14 (10-12) pp 819-820 (2003) |
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V. Vitkova, J. Genova and I. Bivas, “Experimental and Theoretical Study of Lipid Bilayers Permeability and Hidden Area”, C. R. Acad. Bulg. Sci. 55 (10) pp 15-20 (2002) |
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I. Bivas, V. Vitkova, M. D. Mitov, M. Winterhalter, R. Alargova, P. Méléard, P. Bothorel, "Mechanical Properties of Lipid Bilayers, Containing Grafted Lipids", Perspectives in Supramolecular Chemistry, vol. 6, Giant Vesicles, Ed. P. L. Luisi and P. Walde, (John Willey & Sons Ltd., 2000) Chapter 14, pp 207 - 219 |
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V. Doltchinkova, V. Vitkova and R. Nikolov, "Electrokinetic and Light Scattering Properties of Spinach Thylakoids: Effects of Divalent Cations and Polylysine", Comments on Molecular and Cellular Biophysics, 9 (6), pp. 357 – 378 (1999) |
awards:
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Best Poster Prize (13-th ISCMP, Varna, Bulgaria) for the poster entitled: “Tumbling of deformable lipid vesicles containing a viscous polymer solution” (V. Vitkova, M. Mader, T. Biben, T. Podgorski) |
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Best scientific achievement in international collaboration of the Institute of Solid State Physics (BAS) – first place – for the study: “Alamethicin influence on the membrane bending elasticity” (V. Vitkova, P. Méléard, T. Pott and I. Bivas, “Alamethicin influence on the membrane bending elasticity”, Eur. Biophys. J. 35, pp. 281-286 (2006)) |
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Best scientific achievement in international collaboration of the Institute of Solid State Physics (BAS) – first place – for the study: “Micro-macro link in rheology of erythrocyte and vesicle suspensions” (V. Vitkova, M.-A. Mader, B. Polack, C. Misbah and T. Podgorski, “Micro-macro link in rheology of erythrocyte and vesicle suspensions”, Biophys. J. 95 (7) L33-L35, (2008)) |
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Best scientific achievement of the Institute of Solid State Physics (BAS) –
first place – for the study: “Optical anisotropy induced by the electric field
in suspensions of giant lipid vesicles” with authors: V. Vitkova, K. Antonova,
M. D. Mitov, G. Popkirov, T. Tenev, I. Miloushev, Yu. A. Ermakov, and I. Bivas,
(presented in: Europhys. Lett. EPL 89 38004 (2010), J. Phys.: Conf. Ser. 253
012058 (2010), J. Phys.: Conf. Ser. 253 012059 (2010), and at the 9-th
International Frumkin Symposium “Materials and Technologies in Electrochemistry
of the 21-st century”, Moscow 24-29 October 2010) |
collective responsibilities:
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Head of Liquid Crystals Laboratory - ISSP (BAS) - 2017 until now |
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Head of the Division "Soft Matter Physics" - ISSP (BAS) - 2016/17 |
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Scientific secretary of the Division "Soft Matter Physics" - ISSP (BAS) - 2009/16 |
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Coordinator of research projets funded by the National Science Foundation, Bulgaria (contracts MUF-1203/02; DMU03-80/2011; DN08-7/2016) – 2002 until now |
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Coordinator of bilateral research projects with Austria (2009/11), France (2015/16) and Belgium (2009 until now) |
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Coordinator of research projects funded by ISSP - BAS (contracts VK-01-07; VK-01-11) - 2007/11 |
presentations:
Total: 33 scientific conferences, congresses and forums (24 - International and 9 - National)
research projects:
Total: 14 (7 - International and 7 - National)